Hypothyroidism and thyroiditis research

Efficacy of Homeopathic Intervention in Subclinical Hypothyroidism With or Without Autoimmune Thyroiditis in Children: An Exploratory Randomized Control Study.

 

This Indian study was an exploratory, randomised, placebo controlled, single blind trial.

Out of 5059 Indian school children (6-18 years) screened for thyroid disorders, 537 children had subclinical hypothyroidism/autoimmune thyroiditis (SCH/AIT) and 194 consented to participate in the study.

Based on primary outcome measures (TSH and/or antiTPOab) three major groups were formed: Group A- SCH + AIT (n = 38; high TSH with antiTPOab+), Group B- AIT (n = 47; normal TSH with antiTPOab+) and Group C- SCH (n = 109; only high TSH) and were further randomised to two subgroups- verum and control.

Individualised homeopathy or identical placebo was given to the respective subgroups.

162 patients completed 18 months of study. Baseline characteristics were similar in all the subgroups.

The post treatment serum TSH (Group A and C) returned to normal limits in 85.94% of verum and 64.29% of controls (p < 0.006), while serum AntiTPOab titers (Group A and B) returned within normal limits in 70.27% of the verum group and 27.02% of the controls (p < 0.05).

Eight children (10.5%) progressed to overt hypothyroidism (OH) from the control group.

In conclusion, statistically significant declines in serum TSH values and antiTPOab titres indicates that the homeopathic intervention has not only the potential to treat SCH with or without antiTPOab but may also prevent the progression to OH.

Chauhan, V.K.; Manchanda, 2014

 

 

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